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Garfield's work as a computer analyst and leader of a team of engineers, scientists, and support staff on the Apollo 11 project first led to his discovery of the dynamics of peak performance. For over thirty years, Garfield has conducted a continuous study of business high achievers and their companies. As founder and CEO of Shanti Project, a volunteer organization, he inspired service excellence for peak performers of another kind: patients and families facing life-threatening illness. For his work with Shanti, Garfield was named "National Activist of the Year."

Garfield is the cofounding editor (along with Stephen Covey and Ken Blanchard) of the executive newsletter Executive Excellence, is a strategy adviser to business leaders, and is one of the country's most-requested public speakers. He is a clinical professor at the University of California Medical School in San Francisco and is CEO of the Charles Garfield Group, a consulting and educational firm specializing in organizational strategies for superior service, quality, and performance.